Golden Staph Vaccine Study

Staphylococcus aureus (staph) is a bacteria (germ) that lives on the skin and mucous membranes (eg. nose, throat, body cavities) of a large proportion of the population, without causing any problems.  However, sometimes staph can avoid the body’s immune defence to cause disease ranging from mild skin infections to more severe infections. It is one of the most common causes of healthcare-associated infection (eg. in hospitals). Staph infection can result in longer treatment and longer hospitalisation for those affected. 

 

Vaccines can help the body to fight off germs, and this investigational vaccine may or may not help protect against staph. This is the first time this vaccine was given to humans to see how safe it is, and to check for any side effects.  This study will also help  decide what the best dose (amount) of vaccine is to give people in the future.  We also measured how many antibodies (special proteins) people make as part of their immune response to the vaccine.