Selected recent publications (* indicates equal contributions):

2005
White, J.K., Mastroeni, P., Popoff, J-F., and Blackwell, J.M. (2005) Slc11a1-mediated resistance to Salmonella enterica serovar Typhimurium and Leishmania donovani infections does not require functional inducible nitric oxide synthase activity or phagocyte oxidase activity.  Journal of Leukocyte Biology, 77, 311-320.

 

Jamieson, S.E., White, J.K.,  Pask, R., Smith, A.N., Brayne, C., Evans, J.G., Xuereb, J., Cairns, N.J., Rubinsztein, D.C. and Blackwell, J.M. (2005) Candidate gene association study of solute carrier family 11a members 1 (SLC11A1) and 2 (SLC11A2) genes in Alzheimer's disease.  Neuroscience Letters, 374, 124-125.

 

Dubaniewicz, A., Jamieson, S.E., Fakiola, M., Dubaniewicz, N., Miller, E.N. and Blackwell, J.M. (2005) Association between SLC11A1 (formerly NRAMP1) and the risk of sarcoidosis in Poland.  European Journal of Human Genetics, 13, 829-834.

 

Stober, C.B. Lange, U., Roberts, M.T.M., Alcami, A. and Blackwell, J.M. (2005) IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection.  Journal of Immunology, 175, 2517-2524.  

 

Roberts, M.T.M., Stober, C.B., McKenzie, A.N. and Blackwell, J.M. (2005) IL-4 and IL-10 collude in vaccine failure for novel exacerbatory antigens in murine Leishmania major infection.  Infection and Immunity, 73, 7620-7628.

 

Ivens, A.C, Peacock, C.S., Worthey, E.A., Murphy, L., Aggarwal, G., Berriman, M., Sisk, E., Hertzfowler, C., Quail, M.A., Harris, D., Rajandream, M-A., Davies, R.M., Aert, R., Andersson, B., Anupama, A., Attipoe, P., Bason, N., Bauser, C., Beck, A., Beverley, S.M., Bianchettin, G., Borzym, K., Bothe, G., Bruschi, C.V., Collins, M., Cadag, E., Ciarloni, L., Clayton, C., Coulson, R.M.R., Cronin, A., Cruz, A.C., r De Gaudenzi, J., Dobson, D.E., Duesterhoeft, A., Fazelina, G., Fosker, N., Frasch, A.C., Fraser, A., Fuchs, M., Gabel, C., Goble, C., Goffeau, A., Hilbert, H., Horn, D., Huang, Y., Klages, S., Knights, A., Kube, M., Larke, N., Litvin, L., Lord, A., Louie, T., Marra, M., Masuy, D., Matthews, K., Michaeli, S., Mottram, J.C., Mueller-Auer, S., Munden, H., Nelson, S., Nilsson, D., Norbertczak, H., Oliver, K., O'Neill, S., Pentony, M., Pohl, T.M., Price, C., Purnelle, B., Rabbinowitsch, E., Reinhardt, R., Rieger, M., Rinta, J., Robben, J., Robertson, L., Ruiz, J., Rutter, S., Saunders, D., Schaefer, M., Schein, J., Schwartz, D.C., Seeger, K., Seyler, A., Sharp, S., Shin, H., Sivam, D., Squares, R., Squares, S., Tosato, V., Tram, A-N., Vogt, C., Volckaert, G., Wambutt, R., Warren, T., Wedler, H.,  Woodward, J., Zhou, S., Zimmermann, W., Smith, D.F., Blackwell, J.M., Stuart, K.D., Barrell, B. and Myler, P.J. (2005)  The genome of the kinetoplastid parasite, Leishmania major. Science, 309, 436-442.

2006

Stober, C.B. Lange, U., Roberts, M.T.M., Gilmartin, B., Francis, R., Almeida, R., Peacock, C.S., McCann, S. and Blackwell, J.M. (2006) From genome to vaccines for leishmaniasis: Screening 100 novel vaccine candidates against murine Leishmania major infection.  Vaccine, 24, 2602-2616.

 

Wheeler, E., Miller, E.N., Peacock, C.S., Donaldson, I.J., Shaw, M.-A., Jamieson, S.E., Blackwell, J.M. and Cordell, H.J. (2006) Genome-wide scan for loci influencing quantitative immune response traits in the Belem Family Study: comparison of methods and summary of results.  Annals of Human Genetics, 70, 78-97.  

 

Castellucci, L., Guimaraes, L., Lessa, M., Lessa, H., Ribeiro, S., Reale, J., Oliveira, J., Henezes, E., Hagalliaes, A., Noronha, E., Wilson, M.E., Duggal, P., Beatty, T., Jeronimo, S., Jamieson, S.E., Blackwell, J.M., de Jesus, A. and Carvalho, E. (2006) Interleukin 6 -174 G/C promoter polymorphism influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil.  Journal of Infectious Diseases, 194, 519-527.

2007

Jamieson*, S.E., Miller*, E.N., Peacock, C.S., Fakiola, M., Jeronimo, S., Wilson, M.E., Bales, A., Shaw, M-A., Silveira, F., Shaw, J.J. and Blackwell, J.M. (2007) Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazilians.  Genes and Immunity, 8, 84-90.

 

Salih, M.A., Ibrahim, M.E., Blackwell, J.M., Miller, E.N., Khalil, E.A.G., ElHassan, A.M., Musa, A.M. and Mohamed, H.S. (2007) IFNG and IFNGR1 gene polymorphisms and susceptibility to post kala-azar dermal leishmaniasis in Sudan.  Genes and Immunity, 8, 75-78.
Stober, C.B. Lange, U., Roberts, M.T.M., Alcami, A. and Blackwell, J.M. (2007) Heterologous prime-boosting with DNA and modified vaccinia virus Anakara expressing tryparedoxin peroxidase promotes long-term memory against Leishmania major in susceptible BALB/c mice.  Infection and Immunity, 75, 852-860.  

 

Miller, E.N.*, Fadl, M.*, Mohamed, H.S., El Zein, A., Jamieson, S.E., Cordell, H.J., Peacock, C.S., Fakiola, M., Raju, M., Khalil, E.A., Elhassan, A., Musa, A.M., Ibrahim, M.E. and Blackwell, J.M. (2007) Y chromosome lineages tag village-specific genes on chromosomes 1p22 and 6q27 that control visceral leishmaniasis in The Sudan.  PLoS Genetics, 3 (5): 679-688.

 

Bayele, H.K., Peyssonnaux, C., Giatromanolaki, A., Arrais-Silva, W.A., Collins, H., Giorgio, S., Koukourakis, M., Nizet, V., Blackwell, J.M., Johnson, R.S. and Srai, S.K.S. (2007) HIF-1α regulates heritable variation in SLC11A1 expression phenotypes relevant to innate immunity and inflammation.  Blood, 110, 3039-3048.  
Johnson, C.M.,  Traherne, J.A, Jamieson, S.E., Tremelling, M. Parkes, M., Blackwell, J.M. and Trowsdale, J. (2007) Analysis of the BTNL2 truncating splice site mutation in tuberculosis, leprosy and Crohn’s disease.  Tissue Antigens, 69, 236-241.

 

Stober, C.B., Brode, S., White, J.K., Popoff, J-F., Blackwell, J.M. (2007) Slc11a1 (formerly Nramp1) is expressed in dendritic cells and influences MHC class II expression and antigen presenting cell function.  Infection and Immunity, 75, 5059-5067.

 

Jeronimo, S.M.B., Holst, A.K.B., Jamieson, S.E., Francis, R., Martins, D.R.A., Ettinger, N.A., Nascimento, E.Y., Miller, E.N., Murray, J.C., Duggal, P., Beaty, T., Blackwell, J.M.* and Wilson, M.E.* (2007) Genes at human chromosome 5q31.1 regulate delayed type hypersensitivity responses associated with Leishmania chagasi infection.  Genes and Immunity, 8, 539-551.  

 

Jeronimo, S.M.B., Duggal, P., Ettinger, N.A, Nascimento, E.Y., Monteiro, G.R., Cabral, A.P., Pontes, N.N., Lacerdo, H.G., Queiroz, P.V., Gomes, C.E.M., Pearson, R.D., Blackwell, J.M., Beaty, T. and Wilson, M.E. (2007) Genetic predisposition to self-curing infection with the protozoan Leishmania chagasi: a genomewide scan.  Journal of Infectious Diseases, 196, 1261-1269.  

 

Techau, M.E., Valdez-Taubas, J., Popoff, J-F., Francis, R., Seaman, M. and Blackwell, J.M. (2007) Evolution of differences in transport function in Slc11a family members.  Journal of Biological Chemistry, 282, 35646-35656.

 

Peacock, C.S., Seeger, K., Harris, D., Murphy, L., Ruiz, J.C., Quail, M.A., Peters, N., Adlem, E., Tivey, A., Aslett, M., Kerhornou, A., Ivens, A., Fraser, A., Rajandream, M.A., Carver, T., Norbertczak, H., Chillingworth, T., Hance, Z., Jagels, K., Moule, S., Ormond, D., Rutter, S., Squares, R., Whitehead, S., Rabbinowitsch, E., Arrowsmith, C., White, B., Thurston, S., Bringaud, F., Baldauf, S.L., Faulconbridge, A., Jeffares, D., Depledge, D.P., Oyola, S.O., Hilley, J.D., Brito, L.O., Tosi, L.R., Barrell, B., Cruz, A.K., Mottram, J.C., Smith, D.F. and Berriman, M. (2007) Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nature Genetics, 39, 839-847.

2008

Jamieson, S.E., de Roubaix, L-A., Cortina-Borja, M., Tan, H.K., Mui, E., Mack, D., Cordell, H.J., Kirisits, M.J., Miller, E.N., Peacock, C.S., Hargrave, A.C., Coyne, J.J., Boyer, K., Bessieres, M-H, Buffolano, W., Ferret, N.,  Franck, J., Kieffer, F., Meier, P., Nowakowska, D.E., Paul, M., Peyron, F., Stray-Pedersen, B., Thulliez, P., Wallon, M., Petersen, E., McLeod, R., Gilbert, R.E. and Blackwell , J.M. (2008) COL2A1 and ABCA4 are epigenetically modified and associated with congenital toxoplasmosis.  PLoS ONE, in press.

Recent reviews

Burgner, D., Jamieson S.E. and Blackwell, J.M. (2006) Genetic susceptibility to infectious diseases: big is beautiful and big will be even better? Lancet Infectious Diseases, 6, 653-663.

 

Smith, D.F., Peacock, C.S. and Cruz, A.K. (2007) Comparative genomics: from genotype to disease phenotype in the leishmaniases. International Journal of Parasitology, 37, 1173-1186.

 

Peacock, C.S. (2007) The practical implications of comparative kinetoplastid genomics. SEB Experimental Biology Series, 58, 25-45.

 

Blackwell, J.M., McMahon-Pratt, D. and Wilson, M.E. (2007) Impact of the Leishmania genome on vaccine development.  In: Myler, P.J. and Fasel, N. (editors) Leishmania: Genomics, Cellular Biology and Control.  Horizon Scientific Press/Caister Academic Press.  ISBN 978-1-904455-28-8.

 

Jamieson, S.E. and Peacock, C.S. (2007) Genomics and infectious diseases: susceptibility, resistance, response, and anti-microbial therapy. In: Genomics and Clinical Medicine (ed. Dhavendra Kumar), Oxford University Press.

 

Blackwell, J.M., Fakiola, M., Ibrahim, M.E., Jamieson, S.E., Jeronimo, S.B., Miller, E.N., Mishra, A., Mohamed, H.S., Peacock, C.S., Raju, M., Sundar, S. and Wilson, M.E. (2008) Genetics and visceral leishmaniasis: of mice and men.  Parasite Immunology, in press.